“Translating Stem Cell Discoveries” Featuring Dr. Ilyas Singeç
On this episode of the Stem Cell Podcast, Dr. Ilyas Singeç from National Center for Advancing Translational Sciences discusses standardizing stem cell differentiation, high-throughput cell culture, personalized medicine, and the potential for biomanufacturing in space.
Dr. Ilyas Singeç is the Director of the Stem Cell Translation Laboratory at the National Center for Advancing Translational Sciences, where he leads a group of scientists working to address efficiency, reproducibility, scalability, and other roadblocks in the translation of iPSCs into therapies. He discusses standardizing stem cell differentiation, high-throughput cell culture, personalized medicine, and the potential for biomanufacturing in space.
Dr. Ilyas Singeç is an expert on all things stem cell biomanufacturing at NIH NCATS. His research group has recently published a number of high-profile papers focused on improving industrial scaling of stem cell production as well as cell survival.
Dr. Arun Sharma, host
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This Episode's Stem Cell Roundup:
- – Scientists generated blastoids, performed single-cell analysis of the trophectoderm, epiblast, and primitive endoderm, and implanted them into open-faced endometrial organoids.
- – Pancreatic endoderm cells implanted in patients with type 1 diabetes were well tolerated and induced meal-regulated insulin secretion.
- – Stimulating YAP activity promotes regeneration of mouse and human salivary gland cells after injury.
- – Scientists developed a human multilineage iPSC-derived organoid that recapitulates cooperative cardiac and gut development and maturation.
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