Cancer Research
Cancer research is a complex, multifaceted field, in which researchers are studying a range of cancer types and applications, from solid tumors to blood cancers to immuno-oncology.
Below is a collection of resources to help you with your cancer research.
Featured
Production of Chimeric Antigen Receptor T Cells
This free Nature Protocols Wallchart summarizes the processes involved in producing CAR T cells for therapy.
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Non-Viral CRISPR Knock-In Anti-B7-H3 CAR-T Cells Are Amenable for Treatment of Subtypes of Small Cell Lung CancerIn this webinar, Scientist Vimal Keerthi discusses his work on identifying CD276 (B7-H3) overexpression in primary human SCLC and developing a non-viral CRISPR-Cas9 knock-in (CKI) based platform against B7-H3 to manufacture CAR T cells for the treatment of SCLC. He demonstrates the feasibility of this CAR T manufacturing platform and how this provides a blueprint for immediate clinical translation, overcoming the bottleneck of viral vector production.<br><br>This webinar is part of the “Translational T Cell Talks: Scaling for the Future†event hosted in collaboration with Scientist.com on June 11, 2024. <a href="/translational-t-cell-talks-2024">View the rest of the talks and read the Q&A transcripts.</a> -
How to Optimize Your T Cell Therapy Workflow—Without the Use of Serum or Feeder CellsIn this talk, Dr. Dominika Nackiewicz introduces how º£½ÇÆƽâ°æ Technologies can help optimize your T cell cultures with robust, high-performance products and expert support. You will learn how to generate high yields of functional T cells for cell therapy development and manufacturing using the new GMP ImmunoCultâ„¢ medium and activators. She will also discuss efficient gene editing strategies using the new CellPoreâ„¢ Transfection System and solutions for T cell generation from pluripotent stem cells or hematopoietic stem and progenitor cells.<br><br>This webinar is part of the “Translational T Cell Talks: Scaling for the Future†event hosted in collaboration with Scientist.com on June 11, 2024. <a href="/translational-t-cell-talks-2024">View the rest of the talks and read the Q&A transcripts.</a> -
Advances in Point-of-Care Cell Engineering—What Are You Feeding Your CAR T Cells?In this webinar, Dr. Julian J. Lum discusses key factors to consider when choosing metabolic assays and how they can be used to assess cell function. Additionally, he discusses the metabolic characteristics of different commercially available cell culture media formulations as well as the importance of assessing the array of media products and their impact on metabolism.<br><br>This webinar is part of the “Translational T Cell Talks: Scaling for the Future†event hosted in collaboration with Scientist.com on June 11, 2024. <a href="/translational-t-cell-talks-2024">View the rest of the talks and read the Q&A transcripts.</a> -
º£½ÇÆƽâ°æ Journal Club: Mechanisms of Glioblastoma ResistanceDr. Jason Hamlin discusses the role of brain tumor stem cells in the development of glioblastoma treatment resistance -
How to Generate Uniform, Size-Controlled 3D Spheroid Cultures with AggreWellâ„¢ Microwell PlatesLearn how AggreWellâ„¢ Microwell Plates work to generate large numbers of uniform, size-controlled 3D cell culture spheroids for many areas of research, including cancer, stem cells, drug discovery and more -
CAR T Cell Manufacturing Workflow: Isolation, Activation and ExpansionLearn about human T cell isolation, activation, and expansion workflow for cell therapy
