Phenotyping Midbrain Organoids and Neurons for Studying Parkinson’s Disease and Therapeutic Discovery
Induced pluripotent stem cell (iPSC)-derived neural models enable researchers to work with and visualize living human neuronal tissue that recapitulates distinct regions of the human brain.
In this webinar, Dr. Thomas Durcan outlines how midbrain organoids and dopaminergic (DOPA) neurons can be combined with automated high-content imaging and single-cell flow cytometry workflows to profile cells within these 2D and 3D structures at the single-cell level. He describes the growth and development of these models over time and explains how single-cell phenotyping provides a better understanding of the complexities and cell compositions within these brain tissues. By combining these advanced technologies, researchers can gain a better understanding of Parkinson’s disease and leverage organoids to evaluate novel therapeutic approaches.
In this webinar, Dr. Thomas Durcan outlines how midbrain organoids and dopaminergic (DOPA) neurons can be combined with automated high-content imaging and single-cell flow cytometry workflows to profile cells within these 2D and 3D structures at the single-cell level. He describes the growth and development of these models over time and explains how single-cell phenotyping provides a better understanding of the complexities and cell compositions within these brain tissues. By combining these advanced technologies, researchers can gain a better understanding of Parkinson’s disease and leverage organoids to evaluate novel therapeutic approaches.
Publish Date:
March 03, 2025
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