海角破解版

Dr. Caroline Lindemans

Dr. Caroline Lindemans talks about her research on the role of innate immune cells in intestinal stem cell maintenance

Dr. Caroline Lindemans discusses her work on intestinal repair following injury caused by graft versus host disease. In her research, Dr. Lindemans utilized intestinal epithelial organoids to demonstrate the effects of IL-22 on the stem cell niche of intestinal crypts and its contribution to epithelial repair following injury.
In this episode of 海角破解版's Organoids Podcast we ask Dr. Lindemans:

  • 鈥淲hy use organoids as a model system?鈥
  • 鈥淲hat were some challenges of co-culturing organoids with innate lymphoid cells?鈥
  • 鈥淗ow did you standardize the metrics, such as size, for assessing organoid cultures?鈥
  • 鈥淲hat are some advantages and disadvantages to using both animal models and organoid culture?鈥
Publish Date: May 15, 2017